KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL3
All Species:
37.58
Human Site:
T256
Identified Species:
55.11
UniProt:
Q13618
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13618
NP_003581.1
768
88930
T256
M
H
C
L
D
K
S
T
E
E
P
I
V
K
V
Chimpanzee
Pan troglodytes
XP_001167451
757
87889
T245
M
H
C
L
D
K
S
T
E
E
P
I
V
K
V
Rhesus Macaque
Macaca mulatta
XP_001109600
746
86448
T234
M
H
C
L
D
K
S
T
E
E
P
I
V
K
V
Dog
Lupus familis
XP_534586
746
86477
T234
M
H
C
L
D
K
S
T
E
E
P
I
V
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLV5
768
88930
T256
M
H
C
L
D
K
S
T
E
E
P
I
V
K
V
Rat
Rattus norvegicus
Q9JJ31
780
90872
R253
L
R
Y
L
E
T
R
R
E
C
N
S
V
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512511
642
74121
I150
I
S
K
H
M
K
T
I
V
E
M
E
N
S
G
Chicken
Gallus gallus
XP_422620
768
88957
T256
M
H
C
L
D
K
S
T
E
E
P
I
V
K
V
Frog
Xenopus laevis
Q6DE95
768
88933
T256
M
H
C
L
D
K
S
T
E
E
P
I
V
K
V
Zebra Danio
Brachydanio rerio
NP_955985
766
89011
T254
M
H
C
L
D
K
S
T
E
E
P
I
V
K
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
L278
S
K
N
G
L
S
Y
L
H
E
T
T
A
D
V
Honey Bee
Apis mellifera
XP_625079
767
89385
T253
K
H
Y
L
D
E
S
T
E
P
R
I
V
E
V
Nematode Worm
Caenorhab. elegans
Q17391
777
90217
V262
T
E
A
K
I
L
Q
V
M
D
D
V
M
V
A
Sea Urchin
Strong. purpuratus
XP_001178314
675
78472
F183
R
D
C
V
Q
I
S
F
I
D
F
Y
R
D
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
S243
A
H
Y
L
H
S
S
S
E
P
K
L
V
E
K
Baker's Yeast
Sacchar. cerevisiae
P53202
744
86097
E236
I
R
K
L
R
Q
F
E
S
M
L
D
S
S
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.9
97.1
96.8
N.A.
99.4
26.4
N.A.
83.1
99.6
98.5
95.9
N.A.
28.4
77.2
49.6
67
Protein Similarity:
100
98
97.1
96.8
N.A.
99.6
49.4
N.A.
83.3
99.7
99.2
98.3
N.A.
52.4
87.5
69.1
76.9
P-Site Identity:
100
100
100
100
N.A.
100
20
N.A.
13.3
100
100
100
N.A.
13.3
60
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
26.6
100
100
100
N.A.
13.3
73.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.5
46.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
0
0
0
0
0
0
0
0
0
7
0
13
% A
% Cys:
0
0
57
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
7
0
0
57
0
0
0
0
13
7
7
0
13
0
% D
% Glu:
0
7
0
0
7
7
0
7
69
63
0
7
0
19
0
% E
% Phe:
0
0
0
0
0
0
7
7
0
0
7
0
0
0
7
% F
% Gly:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
7
% G
% His:
0
63
0
7
7
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
13
0
0
0
7
7
0
7
7
0
0
57
0
0
0
% I
% Lys:
7
7
13
7
0
57
0
0
0
0
7
0
0
50
7
% K
% Leu:
7
0
0
75
7
7
0
7
0
0
7
7
0
0
0
% L
% Met:
50
0
0
0
7
0
0
0
7
7
7
0
7
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
0
7
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
13
50
0
0
0
0
% P
% Gln:
0
0
0
0
7
7
7
0
0
0
0
0
0
0
0
% Q
% Arg:
7
13
0
0
7
0
7
7
0
0
7
0
7
0
0
% R
% Ser:
7
7
0
0
0
13
69
7
7
0
0
7
7
13
0
% S
% Thr:
7
0
0
0
0
7
7
57
0
0
7
7
0
0
0
% T
% Val:
0
0
0
7
0
0
0
7
7
0
0
7
69
7
63
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
19
0
0
0
7
0
0
0
0
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _